Airglow observations and modeling of F region depletion zonal velocities over Christmas Island

We report image measurements of plasma depletions in the equatorial F region ionosphere over Christmas Island (2.1°N, 157.4°W; dip latitude 2.8°N) in the central Pacific Ocean. The observations were made during the equinox period, September‐October 1995, using a Utah State University CCD imaging system filtered to observe thermospheric O I (630.0 nm) airglow emissions centered at ∼280 km altitude. Well‐defined magnetic field‐aligned depletions were observed on 18 nights during the campaign, including strong postmidnight fossilized structures, enabling detailed measurements of their morphology and dynamics. The number of depletions was influenced by their initial onset times and their persistence. The separations between adjacent depletions ranged from ∼150 to ∼250 km in good agreement with prior observations from other sites. However, measurements of their eastward zonal drift speeds indicated normal behavior peaking around 90–100 m/s prior to local midnight, with exceptionally high velocities, ∼80 m/s during the postmidnight period that persisted until dawn. These results differ markedly from optical measurements at similar equatorial latitudes but at different longitude sectors, suggesting that the zonal drift velocities can have a significant longitudinal dependence. Model drift velocities calculated using a simple electric field model with winds defined by the horizontal wind model (HWM‐07) produced an eastward drift throughout the night, but their postmidnight magnitudes were much smaller than observed. Using a modified HWM‐07 wind field, a basic nighttime trend similar to the Christmas Island trend was successfully obtained

Simultaneous observations of equatorial F-region plasma depletions over Brazil during the Spread-F Experiment (SpreadFEx)

From September to November 2005, the NASA Living with a Star program supported the Spread-F Experiment campaign (SpreadFEx) in Brazil to study the effects of convectively generated gravity waves on the ionosphere and their role in seeding Rayleigh-Taylor instabilities, and associated equatorial plasma bubbles. Several US and Brazilian institutes deployed a broad range of instruments (all-sky imagers, digisondes, photometers, meteor/VHF radars, GPS receivers) covering a large area of Brazil. The campaign was divided in two observational phases centered on the September and October new moon periods. During these periods, an Utah State University (USU) all-sky CCD imager operated at São João d'Aliança (14.8° S, 47.6° W), near Brasilia, and a Brazilian all-sky CCD imager located at Cariri (7.4° S, 36° W), observed simultaneously the evolution of the ionospheric bubbles in the OI (630 nm) emission and the mesospheric gravity wave field. The two sites had approximately the same magnetic latitude (9–10° S) but were separated in longitude by ~1500 km. <br><br> Plasma bubbles were observed on every clear night (17 from Brasilia and 19 from Cariri, with 8 coincident nights). These joint datasets provided important information for characterizing the ionospheric depletions during the campaign and to perform a novel longitudinal investigation of their variability. Measurements of the drift velocities at both sites are in good agreement with previous studies, however, the overlapping fields of view revealed significant differences in the occurrence and structure of the plasma bubbles, providing new evidence for localized generation. This paper summarizes the observed bubble characteristics important for related investigations of their seeding mechanisms associated with gravity wave activity

Adapting Livestock Production Systems to Climate Change in Nepal: Challenges and Opportunities

To assess climate change impacts and identify challenges and opportunities for livestock climate change adaption, we conducted a comprehensive study in the Thulokhola watershed of Nuwakot district in Nepal from June 1, 2011 to January 31, 2013. We established nine community livestock groups (CLGs) consisting of 51 members and trained the CLG members in daily livestock record keeping and monitoring surface water quality. Monthly fecal samples from 50 cattle, 50 goats, and 50 buffaloes were collected for the determination of gastrointestinal parasites. Soil and fodder samples were also collected and analyzed. Group discussions, Participatory Rural Appraisals, and full-fledged household survey of 97 households were done. A survey of 41 water sources in the watershed was also conducted. While 85.3 % of the water sources have either dried up or decreased in flow in recent years, drought conditions had great toll on agricultural production. Prevalence rates of helminthes on goats, cattle, and buffalo was 53.8%, 31.32%, and 23.52%, respectively, and animal deaths were remarkably high. Declining pregnancy rates on livestock along with waning supply of fodder and forages and poor soil quality were additional major problems. Although local communities have undertaken several measures including adding new breed, destocking, purchasing fodder and forages, and planting grasses for livestock climate change adaptation, the problems of animal health, breeding conditions, soil fertility, forest degradation, increasing women workload, and water shortages were largely unaddressed. Opportunities for livestock climate change adaptation in Nepal include agroforestry intervention, groundwater utilization, rainwater harvesting, enhancing feed efficiency, and community capacity-building

Cognitive dysfunction in naturally occurring canine idiopathic epilepsy

Globally, epilepsy is a common serious brain disorder. In addition to seizure activity, epilepsy is associated with cognitive impairments including static cognitive impairments present at onset, progressive seizure-induced impairments and co-morbid dementia. Epilepsy occurs naturally in domestic dogs but its impact on canine cognition has yet to be studied, despite canine cognitive dysfunction (CCD) recognised as a spontaneous model of dementia. Here we use data from a psychometrically validated tool, the canine cognitive dysfunction rating (CCDR) scale, to compare cognitive dysfunction in dogs diagnosed with idiopathic epilepsy (IE) with controls while accounting for age. An online cross-sectional study resulted in a sample of 4051 dogs, of which n = 286 had been diagnosed with IE. Four factors were significantly associated with a diagnosis of CCD (above the diagnostic cut-off of CCDR ≥50): (i) epilepsy diagnosis: dogs with epilepsy were at higher risk; (ii) age: older dogs were at higher risk; (iii) weight: lighter dogs (kg) were at higher risk; (iv) training history: dogs with more exposure to training activities were at lower risk. Impairments in memory were most common in dogs with IE, but progression of impairments was not observed compared to controls. A significant interaction between epilepsy and age was identified, with IE dogs exhibiting a higher risk of CCD at a young age, while control dogs followed the expected pattern of low-risk throughout middle age, with risk increasing exponentially in geriatric years. Within the IE sub-population, dogs with a history of cluster seizures and high seizure frequency had higher CCDR scores. The age of onset, nature and progression of cognitive impairment in the current IE dogs appear divergent from those classically seen in CCD. Longitudinal monitoring of cognitive function from seizure onset is required to further characterise these impairments

Spatial and Temporal Trends of Global Pollination Benefit

Pollination is a well-studied and at the same time a threatened ecosystem service. A significant part of global crop production depends on or profits from pollination by animals. Using detailed information on global crop yields of 60 pollination dependent or profiting crops, we provide a map of global pollination benefits on a 5′ by 5′ latitude-longitude grid. The current spatial pattern of pollination benefits is only partly correlated with climate variables and the distribution of cropland. The resulting map of pollination benefits identifies hot spots of pollination benefits at sufficient detail to guide political decisions on where to protect pollination services by investing in structural diversity of land use. Additionally, we investigated the vulnerability of the national economies with respect to potential decline of pollination services as the portion of the (agricultural) economy depending on pollination benefits. While the general dependency of the agricultural economy on pollination seems to be stable from 1993 until 2009, we see increases in producer prices for pollination dependent crops, which we interpret as an early warning signal for a conflict between pollination service and other land uses at the global scale. Our spatially explicit analysis of global pollination benefit points to hot spots for the generation of pollination benefits and can serve as a base for further planning of land use, protection sites and agricultural policies for maintaining pollination services

Molecular Imaging of Pulmonary Tuberculosis in an Ex-Vivo Mouse Model Using Spectral Photon-Counting Computed Tomography and Micro-CT

Assessment of disease burden and drug efficacy is achieved preclinically using high resolution micro computed tomography (CT). However, micro-CT is not applicable to clinical human imaging due to operating at high dose. In addition, the technology differences between micro-CT and standard clinical CT prevent direct translation of preclinical applications. The current proof-of-concept study presents spectral photon-counting CT as a clinically translatable, molecular imaging tool by assessing contrast uptake in an ex-vivo mouse model of pulmonary tuberculosis (TB). Iodine, a common contrast used in clinical CT imaging, was introduced into a murine model of TB. The excised mouse lungs were imaged using a standard micro-CT subsystem (SuperArgus) and the contrast enhanced TB lesions quantified. The same lungs were imaged using a spectral photoncounting CT system (MARS small-bore scanner). Iodine and soft tissues (water and lipid) were materially separated, and iodine uptake quantified. The volume of the TB infection quantified by spectral CT and micro-CT was found to be 2.96 mm(3) and 2.83 mm(3), respectively. This proof-of-concept study showed that spectral photon-counting CT could be used as a predictive preclinical imaging tool for the purpose of facilitating drug discovery and development. Also, as this imaging modality is available for human trials, all applications are translatable to human imaging. In conclusion, spectral photon-counting CT could accelerate a deeper understanding of infectious lung diseases using targeted pharmaceuticals and intrinsic markers, and ultimately improve the efficacy of therapies by measuring drug delivery and response to treatment in animal models and later in humans

Climatology of early night equatorial spread F over Jicamarca

We use radar observations from 1996 to 2006 to study the climatology of postsunset equatorial 3-m spread F irregularities over Jicamarca during all seasons. We show that the spread F onset times do not change with solar flux and that their onset heights, which occur near the altitude of the evening F region velocity vortex, increase linearly from about 260 to 400 km from solar minimum to solar maximum. Higher onset heights generally lead to stronger radar echoes. During the equinox, spread F onset occurs near vertical drift evening reversal times, while during the December solstice, they occur near the drift reversal times close to solar minimum and near the time of the prereversal velocity peak for high solar flux conditions. On average, radar plume onset occurs earlier with increasing solar flux in all seasons. Plume onset and peak altitudes increase with solar activity, and the peak heights are generally highest during the equinox. The F region upward drift velocities that precede spread F onset increase from solar minimum to solar maximum and are approximately proportional to the maximum prereversal drift peak velocities